לוח אפשרויות קריירה - הדרך החכמה להייטק

a global biotech company is looking for Preclinical Research Manager
Job Summary:
Management of research projects (in vitro, in vivo) at early stages of preclinical developmental phases our pipeline anti-cancer treatments (mechanism of action, proof of concept and pharmacology), in coordination with team members and while supporting additional team projects.
Duties & Responsibilities:
In-vitro:
The individual will design, perform and manage studies to understand the mechanism of action and proof of concept of various drugs, and as such, will be responsible for the following:
Design, execute, analyze and interpret studies done in order to assess the role of various agents in the treatment of bladder and other cancers
Conduct in vitro analysis of immune activation markers, biomarkers, cell assays (primary cells and cell lines), gene/protein expression, etc. in response to small and large molecules
Maintain and demonstrated a high level of professional expertise through familiarity with common research practices in cancer biology and cancer immunology, relevant laboratory procedure, industry best practices for in vitro work, results analysis, scientific literature reviews, clinical and business-related material, relevant IP
Present project results and development status in team and company meetings


In-vivo:
The individual will manage or take an integral part in the following activities:
Design animal studies and select endpoints for proof of concept and pharmacology assessment of small and large molecules
Manage and monitor animal studies conducted at CROs. Communicate with sub-contractors, CROs and other test sites to oversee technical stuff during company's experiments
Write protocols, reports, summaries, and presentations of the results of such studies
Conduct literature and scientific searches to identify best models for analysis
Help in the design and management of studies owned by other department members

דרישות:
List of qualifications
" Ph.D in cancer immunology preferred (optional: immunology/cancer biology)
" Experience in preclinical work done during early pharmaceutical development (minimum of 3 years)
" Prior experience in conducting (hands on), monitoring and managing in-vitro studies (e.g. cell-based assays [primary cells and cell lines], FACS, ELISA, microcopy, etc.), is a must
" Previous experience with nonclinical CROs both local and abroad
" Previous experience with local drug delivery is a benefit
" Experience in scientific and technical writing. Proven ability to perform critical scientific reviews and presentations
" Capable of designing, executing, analyzing, interpreting, and reporting studies according to common pharmaceutical requirements
" Creative, thinker, excels in the face of challenges
" Able to work independently but at the same time, team oriented, collaborative, with excellent personal relationships, highly motivated and with high work ethics
" Ability to effectively prioritize and execute tasks in a high-pressure environment
" Can conform to shifting priorities, demands and timelines, through analytical and problem-solving capabilities
" Self and fast learner, multitasked, punctual and accurate with keen attention to details and excellent organizational skills
" Excellent proficiency in MS office applications
" English – fluent, excellent writing, reading, and speaking abilities
" Ability to travel abroad according to need